Our law firm is currently handling lawsuits on behalf of individuals who have been injured after being treated with proton pump inhibitors (PPIs). Lawsuits against the manufacturers of PPIs claim that long-term use of this class of medication may be linked to cardiovascular disease, kidney disease, and gastrointestinal cancer, some of which have led to death.
PPI medications are prescribed to over 15 million Americans per year. They are used to treat gastrointestinal conditions, such as gastroesophageal reflux disease and H-pylori. PPIs work by reducing acid in the stomach. PPIs include over-the-counter brand names Nexium, Prilosec, and Prevacid. Studies suggest that alternatives to PPI inhibitors, such as H2 blockers, may be just as effective in treating gastrointestinal ailments.
Long-term use of PPIs may have fatal complications. A study published in the medical journal, BMJ, verified that taking PPIs over many years is unsafe. Some research has linked PPIs to chronic kidney disease and other studies have shown that PPIs may cause dementia, bone fractures, and heart disease.
Lawsuits have been filed against PPI manufacturers AstraZeneca, Takeda, and Pfizer for failure to warn consumers about the risks of PPIs. Many of the 15,000 lawsuits claim that consumers were not fully informed about the association between PPIs and kidney and cardiovascular damage. In August 2017, lawsuits against PPI manufacturers were consolidated in a multidistrict litigation in the District of New Jersey. Since its consolidation, the number of lawsuits has grown rapidly. As of 2021, nine bellwether cases have been announced in New Jersey. Today, PPI litigation is one of the largest mass litigations in the country.
PPIs present serious risks of chronic kidney damage or acute interstitial nephritis. Prolonged kidney damage can lead to renal failure and death. PPIs are also linked to cardiovascular disease and cancer.
If you or a loved one has been injured by PPIs, you may recover compensation for any or all of the following:
The Lake Law Firm was founded by Edward J. Lake, Esq., a personal injury lawyer for over 25 years. Our dedicated team of attorneys is committed to seeking justice on behalf of those who have suffered injury or death due to the negligence of others. Our experienced attorneys handle many different types of pharmaceutical drugs, medical devices, and other defective products. The lawyers in our firm have helped collect millions of dollars for their clients. The Lake Law Firm will advocate for you and your rights. Please contact us for a free confidential case evaluation at (888) 274-0139 or submit an inquiry on this page.
Scientific studies have shown a link between chronic PPI use and adverse health conditions.
In 2017, JAMA published a study that concluded that PPIs may result in acute interstitial nephritis. PPI use is also associated with higher incidences of chronic kidney disease.
A 2018 study by the National Institutes of Health on the risks of long-term use of PPIs suggests that chronic use may lead to infections, pneumonia, and dementia in addition to kidney disease. The research noted that PPIs are often taken for extended period of time for off-label uses, which increases the risks of adverse health conditions.